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目的探讨改良微量胃肠内喂养法对喂养不耐受早产儿的临床效果。结论将符合纳入标准的喂养不耐受70例早产儿随机分为对照组和观察组,对照组采用常规微量胃肠道喂养法,观察组按照3h的间隔分别给予温开水、5%葡萄糖水和稀释奶(根据体重稀释)各喂养6次后,如无不耐受给予全奶喂养,比较两组患儿喂养不耐受各项观察指标的变化以及相关并发症的发病率。结果观察组患儿的黄疸持续时间、恢复出生体重时间、胃潴留消失时间、胎便排尽时间、平均出院时间分别为(14.6±2.5)d、(10.1±1.8)d、(5.1±1.2)d、(14.2±2.3)d、(19.2±2.3)d;对照组分别为(19.5±2.1)d、(13.5±1.3)d、(7.4±1.3)d、(18.7±2.5)d、(25.4±2.1)d,两组比较差异均有统计学意义(P<0.001)。在吸吮出现时间和坏死性小肠结肠炎(NEC)、吸入性肺炎等并发症发病率方面,两组比较差异均无统计学意义(P>0.05)。结论与常规微量胃肠道内喂养法相比,改良微量胃肠道内喂养法更能有效地缓解早产儿喂养不耐受症状。
Objective To investigate the clinical effect of modified micro-feeding in gastrointestinal feeding on premature infants who are intolerant. CONCLUSIONS: 70 preterm infants who were intolerant to feeding were randomly divided into control group and observation group. The control group was given routine micro-gastrointestinal feeding. The observation group was given warm water, 5% glucose water and Dilution of milk (diluted according to body weight) after each feeding six times, if no tolerance to give whole milk feeding, comparison of the two groups of children intolerant of various observation indicators of changes and the incidence of complications. Results The duration of jaundice, the time of recovery of birth weight, the disappearance of gastric retention, the time of discharging the meconium, and the average discharge time of the observation group were (14.6 ± 2.5) days, (10.1 ± 1.8) days and (5.1 ± 1.2) days , (14.2 ± 2.3) d and (19.2 ± 2.3) d, respectively. The control group were (19.5 ± 2.1) days and (13.5 ± 1.3) days and 2.1) d, the difference between the two groups was statistically significant (P <0.001). There was no significant difference between the two groups in the incidence of sucking episode and the incidence of necrotizing enterocolitis (NEC) and aspiration pneumonia (P> 0.05). Conclusion Compared with the conventional micro-gastrointestinal feeding, improved micro-gastrointestinal feeding is more effective in alleviating symptoms of feeding intolerance in preterm infants.