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目的:通过对患者血型不规则抗体检测结果进行回顾性分析,探讨血型不规则抗体筛查在临床输血中的意义。方法:将我院自2014年1月至2016年12月间使用微柱凝胶免疫检测技术进行不规则抗体筛查的1782例患者作为研究对象,将抗体呈阳性的患者作进一步的抗体鉴定。结果:不规则抗体筛查阳性的患者有26例(1.46%),女性(0.95%)显著高于男性(0.51%)(X~2=14.352,P<0.05),确认抗体特异性患者有16例,其中Rh系统有9例(56.25%),MNS系统有3例(18.75%),Lewis系统有1例(6.25%),其他3例(18.75%)。结论:在输血前进行不规则抗体的筛查可以对患者体内存在的不规则抗体进行及时的发现,从而为患者选择配合性的血制品,保证输血的安全。
Objective: To retrospectively analyze the detection results of irregular blood group antibody in patients to explore the significance of blood group irregular antibody screening in clinical blood transfusion. Methods: A total of 1782 patients with irregular antibody screening using micro-column gel immunoassay technique from January 2014 to December 2016 in our hospital were selected as the research object, and the antibody positive patients were further identified. RESULTS: Twenty-six patients (1.46%) were found to have irregular antibody screening and were significantly (0.95%) females (0.51%) (X 2 = 14.352, P <0.05) There were 9 cases (56.25%) in Rh system, 3 cases (18.75%) in MNS system, 1 case (6.25%) in Lewis system and 3 cases (18.75%) in Lewis system. Conclusion: The screening of irregular antibodies prior to transfusion can detect the presence of irregular antibodies in patients timely, so as to select the compatible blood products for patients and ensure the safety of blood transfusion.