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目的:研究三种不同用药方式对绝经后复发性尿路感染干预的影响。方法:将135例患者随机分为三组,分别给予抗生素,雌激素联合抗生素,小剂量激素联合抗生素三种不同方式的干预,与6个月后进行疗效评价。结果:抗生素组有效率80.00%,雌激素联合抗生素组有效率93.33%,小剂量激素联合抗生素组有效率91.11%,抗生素组与其余两组比较差异具有统计学意义(P<0.05)。雌激素联合抗生素组与小剂量激素联合抗生素组比较差异无统计学意义(P>0.05)。结论:小剂量激素联合抗生素是一种对绝经后复发性尿路感染有效的干预手段。
Objective: To study the effects of three different modes of medication on post-menopausal recurrent urinary tract infection. Methods: One hundred and thirty-five patients were randomly divided into three groups. The patients were given antibiotics, estrogen combined with antibiotics and low dose of hormone combined with antibiotics in three different ways, and the efficacy was evaluated after 6 months. Results: The effective rate was 80.00% in antibiotic group, 93.33% in combined estrogen and antibiotics group, and 91.11% in low - dose steroid combined with antibiotic group. There was significant difference between antibiotic group and the other two groups (P <0.05). There was no significant difference between estrogen combined antibiotic group and low dose hormone combined antibiotic group (P> 0.05). Conclusions: Low-dose steroid combined with antibiotics is an effective intervention for post-menopausal recurrent urinary tract infections.