寻常性天疱疮Pemphigus Vulgaris为一种非感染性疾病。病理特征系棘层细胞松解变性,诊断往往须依据临床体征和组织病理。自Tzanck提出寻常性天疱疮细胞诊断以来,取材都是采取清除疱液,在水疱基底部刮取组织涂片检查的方法。这种方法虽可得到较新鲜的细胞,但细胞变化不明显,作细胞学诊断不理想。 Pemphigus vulgaris is a non-infectious disease. The pathological features of the acanthocytic cells are degeneration, and diagnosis is often based on clinical signs and histopathology. Since Tzanck proposed the diagnosis of pemphigus vulgaris cells, the method was to remove the sputum and scrape the tissue smear on the base of the blister. Although this method can obtain fresher cells, cell changes are not obvious, and cytological diagnosis is not ideal.