论文部分内容阅读
阻止肿瘤细胞扩散与转移的细胞外基质和基底膜屏障 ,主要由结构蛋白 (包括胶原蛋白、层粘蛋白与玻璃体结合素等 )和糖氨聚糖 2种成分构成。糖氨聚糖的主要成分是硫酸乙酰肝素蛋白多糖(ｈｅｐａｒａｎｓｕｌｆａｔｅｐｒｏｇｌｙｃａｎ ,ＨＳＰＧ) ,ＨＳＰＧ主要由 1个核心蛋白
The extracellular matrix and the basement membrane barrier, which prevent the spread and metastasis of tumor cells, are mainly composed of two components, structural proteins (including collagen, laminin and vitronectin) and glycosaminoglycans. The main component of glycosaminoglycan is heparansulfateproglycan (HSPG), HSPG mainly consists of a core protein