1二甲双胍是药物治疗糖尿病的基石作为治疗2型糖尿病的经典降糖药物之一,二甲双胍的使用已有半个多世纪的历史,二甲双胍凭借自身独特降糖机制,目前的使用量已位居糖尿病口服降糖药物之首。国际糖尿病联盟(IDF)于2005年在其糖尿病防治指南中指出二甲双胍是治疗2 Metformin is the cornerstone of drug treatment of diabetes as a treatment of type 2 diabetes, one of the classic antidiabetic drugs, the use of metformin for more than half a century of history, metformin with its own unique mechanism of hypoglycemia, the current use of diabetes has been oral Hypoglycemic drugs first. The International Diabetes Federation (IDF) in its guidelines for the prevention and treatment of diabetes in 2005 pointed out that metformin is treatment 2