目前,恶性肿瘤已成为人类死亡的第1位或第2位原因且有逐年上升的趋势[1],严重威胁人类健康和生命,肿瘤病因学成为目前的研究热点之一。糖尿病是一组以慢性血糖水平增高为特征的代谢性疾病,其发病率亦逐年增加,在发达国家已成为继心血管病和肿瘤之后的第三大非传染病[2]。恶性肿 Currently, malignant tumors have become the first or second cause of death in humans and have been increasing year by year, which is a serious threat to human health and life. Cancer etiology has become one of the current research hotspots. Diabetes mellitus is a group of metabolic diseases characterized by an increase in chronic blood glucose levels. The incidence of diabetes mellitus is also increasing year by year. It has become the third largest non-contagious disease after cardiovascular disease and cancer in developed countries [2]. Malignant