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邻苯二甲酸二辛酯(DOP)是一种应用广泛的增塑剂。据文献报道,DOP及其部分同系物对动物睾丸有一定损害。由于锌与雄性动物的生殖机能密切相关,因此,本实验测定了大鼠血清锌和睾丸锌含量,以探讨DOP对锌代谢的影响。材料与方法一、受试物:DOP由长沙有机化工厂提供,为无色油状液体,纯度>99%,比重0.9861。DBP(邻苯二甲酸二丁酯)由湖南益阳油脂化工厂提供,纯度99.2%。二、动物染毒:本实验用Wistar雄性大鼠,体
Dioctyl phthalate (DOP) is a widely used plasticizer. According to the literature, DOP and some of its homologues have some damage to animal testes. Because of the close relationship between zinc and reproductive function in male animals, we measured the contents of serum zinc and testicular zinc in rats to explore the effect of DOP on zinc metabolism. Materials and Methods First, the test substance: DOP provided by the Changsha Organic Chemical Factory, a colorless oily liquid, purity> 99%, the proportion of 0.9861. DBP (dibutyl phthalate) from Hunan Yiyang oil chemical plant to provide purity of 99.2%. Second, animal poisoning: The experiment with Wistar male rats, body