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采用免疫组化技术，对６０例卵巢上皮细胞癌组织进行了Ｐ５３蛋白表达的检测，分析Ｐ５３蛋白表达与卵巢上皮细胞癌病理分级、临床分期、淋巴转移等诸因素间的相关性。结果显示卵巢上皮细胞癌Ｐ５３蛋白表达阳性率为４６６％。Ｐ５３蛋白表达与卵巢上皮细胞癌的病理分级、临床分期、淋巴结转移无显著相关性，但Ｐ５３蛋白强阳性表达的肿瘤均为临床Ⅲ期或Ⅳ期，分化较差，淋巴结有转移的晚期肿瘤。
Immunohistochemistry was used to detect the expression of P53 protein in 60 cases of epithelial ovarian cancer tissues and to analyze the correlation between the expression of P53 protein and the pathological grade, clinical stage and lymphatic metastasis of epithelial ovarian cancer. The results showed that the positive rate of P53 protein expression in epithelial ovarian cancer was 46.6%. P53 protein expression and epithelial ovarian cancer pathological grade, clinical stage, lymph node metastasis was not significantly correlated, but strongly positive P53 protein expression in the clinical stage Ⅲ or Ⅳ, poorly differentiated, advanced lymph node metastasis of the tumor.