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目的探讨无肌病性皮肌炎合并肺间质纤维化临床治疗疗效。方法 21例无肌病性皮肌炎合并肺间质纤维化患者,随机分为观察组(12例)和对照组(9例),对照组患者肺部高分辨率CT影响以网格影和纤维条索影为主;观察组患者则表现为磨玻璃样和蜂窝状病变,比较两组患者临床治疗效果。结果对照组发热8例,干咳7例,Velcro啰音7例,低氧血症7例,慢性肺间疾病(ILD)7例;观察组发热2例,干咳2例,Velcro啰音1例,低氧血症3例,ILD4例,组间ILD病情比较差异有统计学意义(P<0.05)。结论临床上在治疗无肌病性皮肌炎合并肺间质纤维化疾病时,患者肺部高分辨率CT影像与无肌病性皮肌炎之间存在紧密联系,以网格影和纤维条索影为主治疗结果比较明显,磨玻璃样和蜂窝状病变治疗效果较差。
Objective To explore the clinical efficacy of myopathy-free dermatomyositis combined with pulmonary fibrosis. Methods Twenty-one cases of myositis-free dermatomyositis with interstitial fibrosis were randomly divided into observation group (n = 12) and control group (n = 9). The control group had high resolution CT Fibrous cable cable-based; the observation group patients showed ground-glass and honeycomb lesions, the clinical efficacy of the two groups were compared. Results In the control group, there were 8 cases of fever, 7 cases of dry cough, 7 cases of Velcro rales, 7 cases of hypoxemia and 7 cases of chronic pulmonary disease (ILD), 2 cases of fever in observation group, 2 cases of dry cough, 1 case of Velcro rales, There were 3 cases of hypoxemia and 4 cases of ILD. There was significant difference in ILD between the two groups (P <0.05). Conclusion In the treatment of myopathy-free dermatomyositis with pulmonary fibrosis, there is a close relationship between high-resolution CT images of lung and non-myopathy dermatomyositis. Cable-based treatment results were more obvious, ground glass and honeycomb lesion treatment less effective.