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为观察干扰素能否阻止或降低输血后急性丙型肝炎的慢性化率,对26例输血后急性丙肝采用干扰素治疗。另将未采用干扰素治疗的12例作对照观察,现将治疗结果及随访观察报告如下。1 临床资料1.1 病例选择 38例(含对照组12例)输血后急性丙肝均为我院住院和门诊病人,其中男32例,女6例,平均年龄36岁。输血史在1个半月至5个月。血清ALT均增高至正常值的1.5倍以上,HCV-RNA均阳性。诊断符合1995年5月北京会议修订的诊断标准。两组病人年龄、性别、病情具有可比性。
To observe whether interferon could prevent or reduce the rate of acute hepatitis C after transfusion, 26 cases of acute hepatitis C after transfusion were treated with interferon. The other will not use interferon treatment of 12 cases for the control observation, the treatment results and follow-up observations are as follows. 1 Clinical data 1.1 Case Selection 38 cases (including 12 cases of control group) Acute hepatitis C after transfusion are hospitalized and outpatient patients in our hospital, including 32 males and 6 females, mean age 36 years. Blood transfusion in the history of 1.5 months to 5 months. Serum ALT were increased to more than 1.5 times the normal, HCV-RNA were positive. The diagnosis was in accordance with the revised diagnostic criteria of the Beijing meeting in May 1995. Two groups of patients age, gender, disease is comparable.