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【目的】探讨血压对糖尿病合并冠心病患者认知功能的影响。【方法】糖尿病合并冠心病患者106例，根据血压水平分为合并高血压组（DH组，50例）和不合并高血压组（DNH组，56例），根据患者血压控制水平将DN H组患者又分为血压控制良好组（26例）和血压控制不佳组（30例）。以简易精神状态量表（MMSE）、Montreal认知量表（MoCA）及Blessed‐Roth痴呆表（B‐R）评估患者认知功能。【结果】与DNH组相比，DH组患者的MMSE评分、MoCA评分显著降低（ P ＜00．5），而DH组的B‐R评分较DNH组显著增高（ P ＜00．5）；血压控制不佳组MMSE评分、MoCA评分较血压控制良好组显著降低（ P ＜00．5），而B‐R评分显著增高（ P ＜00．5）。收缩压、舒张压脉压、平均动脉压及高血压病程与认知功能均有相关性。【结论】高血压是糖尿病合并冠心病患者认知功能损害的危险因素，适度控制血压可能对2型糖尿病患者的认知功能有一定保护作用。“,”Objective]To investigate the effect of blood pressure on the cognitive function of patients with diabetes mellitus and coronary heart disease [.Methods]A total of 106 diabetic patients complicated with CHD , according to the blood pressure levels were divided into hypertensive groups (DH group) and non‐hypertensive group (DNH group) .According to the level of blood pressure control ,patients with hypertension (DNH group) were re‐divided into good blood pressure control group (26 cases) and poor blood pressure control group (30 cases) .Mini‐mental state examination (MMSE) ,Montreal Cognitive Scale (MoCA ) and Blessed‐Roth dementia table (B‐R) were used to assess cognitive function .[Results]Compared with DNH group , MMSE scores and MoCA scores of DH group were significantly lower ( P <0 0.5) ,while B‐R score of the DH group was significantly higher than that of the DNH ( P <0 0.5) .Between the two subgroups of DNH group , MMSE scores ,MoCA score and B‐R scores of the poor control group were also significantly lower that those of the good control group ( P <0 0.5) ,whereas its B‐R score increased significantly ( P <0 0.5) S.ystolic blood pressure ,diastolic pressure ,pulse pressure ,mean arterial pressure and duration of hypertension were correla‐ted with cognitive function .[Conclusion]Hypertension is a risk factor for cognitive impairment in patients with diabetes mellitus and coronary heart disease ;moderate control of blood pressure may have a protective effect on cognitive function in patients with type 2 diabetes mellitus .