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将83例T2DM患者分为合并下肢动脉病变组(LEAD+组)和不合并下肢动脉病变组(LEAD-组)。结果:LEAD+组年龄(Age)、收缩压(SBP)、甘油三酯(TG)、脂蛋白a[Lp(a)]、全血粘度低切(BVL)、红细胞聚集指数(EAI)、红细胞变形指数水平(EDI)较LEAD-组明显增高;两组的糖化血红蛋白(HbAlc)、舒张压(DBP)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹静脉血糖(FPG)、血清胰岛素(FINS)、全血粘度高切(BVH)、全血粘度中切(BVM)、血浆粘度(ηp)、血沉方程K值(Kesr)、红细胞刚性指数(ERI)及胰岛素抵抗指数(IRI)等差异无统计学意义。LEAD的发生与年龄、SBP、Lp(a)、BVL、EAI、EDI呈正相关。多元逐步回归分析显示。结论:年龄、SBP、Lp(a)、EAI和EDI是糖尿病下肢血管病变的主要危险因素。
83 patients with T2DM were divided into the lower extremity arterial lesion group (LEAD + group) and the lower extremity arterial lesion group (LEAD- group). Results: Age, SBP, TG, Lp (a), low blood viscosity (BVL), erythrocyte aggregation index (EAI), erythrocyte deformation The levels of HbA1c, DBP, TC, HDL-C and LDL-C in the two groups were significantly higher than those in LEAD- LDL-C, FPG, FINS, BVH, BVM, ηp, Kesr, Erythrocyte rigidity index (ERI) and insulin resistance index (IRI) and other differences were not statistically significant. The incidence of LEAD was positively correlated with age, SBP, Lp (a), BVL, EAI and EDI. Multiple stepwise regression analysis showed. CONCLUSIONS: Age, SBP, Lp (a), EAI and EDI are the major risk factors for diabetic lower extremity vascular disease.