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目的探讨非酒精性脂肪性肝病(NAFLD)与颈动脉粥样硬化的关系。方法选取本单位体检人员130例,其中65例诊断非酒精性脂肪性肝病患者为NAFLD组,65例健康者为对照组。采用B超检测颈动脉内膜-中层厚度(IMT),同时测定身高、体重、腰围、血压、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)、甘油三酯、总胆固醇、血糖,计算体质指数(BM I)及胰岛素抵抗指数(HOMA-IR)。结果两组间体重、腰围、体重指数、血压、ALT、AST、血糖、胰岛素抵抗指数差异均有统计学意义,非酒精性脂肪性肝病组IMT较对照组高。结论非酒精性脂肪性肝病与颈动脉粥样硬化密切相关。
Objective To investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and carotid atherosclerosis. Methods 130 cases of this unit were selected, of which 65 cases of non-alcoholic fatty liver disease NAFLD group, 65 cases of healthy control group. The carotid artery intima - media thickness (IMT) was detected by B - ultrasound. Height, weight, waist circumference, blood pressure, alanine aminotransferase (ALT), aspartate aminotransferase Total cholesterol, blood glucose, body mass index (BM I) and insulin resistance index (HOMA-IR). Results There were significant differences in body weight, waist circumference, body mass index, blood pressure, ALT, AST, blood glucose and insulin resistance index between the two groups. IMT in non-alcoholic fatty liver disease group was higher than that in control group. Conclusion Non-alcoholic fatty liver disease is closely related to carotid atherosclerosis.