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目的探讨MPV、FIB、ApoAⅠ等指标在高血压脑梗死患者中的临床意义。方法回顾性分析高血压脑梗死组、单纯高血压组及对照组MPV、FIB、ApoAⅠ、ApoAⅠ/B指标的变化。结果高血压脑梗死组MPV、FIB分别为(13.82±0.73)、(4.19±0.75),明显高于单纯高血压组的(13.22±0.38)、(3.66±0.61)及对照组的(12.41±0.51)、(3.27±0.61),P<0.05;HDL、ApoAⅠ、ApoAⅠ/B分别为(1.02±0.23)、(0.92±0.22)、(0.91±0.24),明显低于单纯高血压组的(1.43±0.31)、(1.26±0.32)、(1.39±0.16)及对照组的(1.61±0.12)、(1.37±0.36)、(1.46±0.21),P<0.05,三组比较具有统计学意义。结论高血压脑梗死患者存在凝血及血脂的异常,早期干预治疗,可减少致残率。
Objective To investigate the clinical significance of MPV, FIB, ApoA Ⅰ in patients with hypertensive cerebral infarction. Methods The changes of MPV, FIB, ApoAⅠ, ApoAⅠ / B in hypertensive cerebral infarction group, simple hypertensive group and control group were retrospectively analyzed. Results The MPV and FIB in hypertensive cerebral infarction group were (13.82 ± 0.73) and (4.19 ± 0.75), respectively, which were significantly higher than those in the hypertensive group (13.22 ± 0.38 and 3.66 ± 0.61 and 12.41 ± 0.51 (1.02 ± 0.23), (0.92 ± 0.22) and (0.91 ± 0.24), respectively, which were significantly lower than those in the hypertension group (1.43 ± 0.61, P <0.05). The levels of HDL, ApoAⅠ and ApoAⅠ / 0.31, 1.26 ± 0.32, 1.39 ± 0.16 and 1.61 ± 0.12, 1.37 ± 0.36, 1.46 ± 0.21 respectively in the control group, P <0.05. The three groups were statistically significant. Conclusion Hypertensive cerebral infarction patients have coagulation and dyslipidemia, early intervention can reduce the morbidity.