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目的：研究心理干预对青年脑卒中患者免疫功能影响的临床意义。方法笔者选取了2011年4月-2013年9月入住我院的45岁以下的脑卒中患者98例，并将其随机分为对照组49例，观察组49例。两组均采用脑卒中后常规治疗和护理。观察组同时实施心理干预。在治疗前、治疗后1个月、治疗后3个月分别测定两组患者血清免疫球蛋白IgA、IgG、IgM、补体C3、C4的水平变化。结果治疗前，两组各免疫指标无显著差异(P >0.05)。1个月后观察组IgA水平显著高于对照组(P 0.05)。3个月后，观察组IgA、C4水平显著高于对照组(P 0.05)。结论心理干预对提高青年脑卒中患者免疫功能有着积极的临床意义。“,”Objective The clinical effects of psychological intervention on immune function of young patients with stroke were investigated. Methods 98 young patients with stroke in our hospital between April 2011 to September 2013 were arranged randomly into control group 49 and case group 49. Both groups were treated with general post-stroke treatment and nurse . And meanwhile only the case group was treated with psychological intervention. Their serum IgA, IgG, IgM, C3and C4 levels were detected respectively in prior-treatment, post-treatment 1 month and post-treatment 3 month. Results Before treatment, both groups showed no significant difference (P >0.05). Post-treatment 1 month, the IgA levels in the case group was significantly higher than those in the control group(P 0.05). Post-treatment 3 month, the values of IgA and C4 were significantly higher in the case group than those in the control group(P 0.05). Conclusion It is clinical y significant for psychological intervention to improve the immune function of young patients with stroke .