1 肝硬化时血液动力学的变化 在肝硬化形成和发展过程中伴随着体内血液动力学的严重紊乱,这种肝硬化特征性循环改变通常称为高动力循环,如心输出量增加、心率加快、血容量增加、全身血管阻力、平均动脉压明显降低、肾血流量减少、高肾素血症及加压系统活性增高。在此之前,内脏系统特别是门脉循环已有明显变化,门脉血流量及血管阻力的增加是形成与维持门脉高压 1 Changes in Hemodynamics During Cirrhosis With severe hemodynamic disturbances in the development and progression of cirrhosis, the characteristic circulatory changes of cirrhosis are commonly referred to as hyperdynamic circulation, such as increased cardiac output and increased heart rate , Increased blood volume, systemic vascular resistance, decreased mean arterial pressure, decreased renal blood flow, increased renin hyperactivity, and increased activity of the pressurized system. Prior to this, the visceral system, especially the portal circulation has been significantly changed, portal blood flow and vascular resistance increase is the formation and maintenance of portal hypertension