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目的探讨美托洛尔治疗慢性充血性心力衰竭影响。方法选择慢性充血性心力衰竭患者80例,上述患者被随机分为观察组和对照组。两组患者均给予血管紧张素转换酶抑制剂、利尿剂、强心类药物等。对照组采用以上常规治疗。观察组在以上治疗基础上给予美托洛尔6.25mg口服,2次/d,患者病情稳定,剂量可增加到12.5mg,2次/d,根据患者具体情况剂量可增加到25～50mg,2次/d。两组患者均治疗12周。治疗结束后评定两组临床效果。结果观察组总有效率为97.5%,对照组总有效率为80.0%,两组总有效率比较,差异有统计学意义(P<0.05)。结论美托洛尔能够显著改善慢性充血性心力衰竭患者临床症状,提高心功能,临床效果显著。
Objective To investigate the effect of metoprolol on chronic congestive heart failure. Methods Eighty patients with chronic congestive heart failure were selected. The above patients were randomly divided into observation group and control group. Two groups of patients were given angiotensin converting enzyme inhibitors, diuretics, cardiac drugs and so on. Control group using the above conventional treatment. The observation group was given metoprolol 6.25mg orally twice a day on the basis of the above treatment, and the patient’s condition was stable. The dosage could be increased to 12.5mg twice daily, which could be increased to 25-50mg according to the patient’s specific conditions. Times / d. Both groups were treated for 12 weeks. After the end of treatment, the clinical effects of both groups were evaluated. Results The total effective rate was 97.5% in the observation group and 80.0% in the control group. The total effective rate in the two groups was statistically significant (P <0.05). Conclusion Metoprolol can significantly improve the clinical symptoms and improve cardiac function in patients with chronic congestive heart failure, the clinical effect is significant.