本文报告作者对疑似急性心肌梗塞(AMI)者静注心得安预防心室颤动(VF)的前瞻性随机对照研究结果。735例患者,其中364例心得安组,371例对照组;年龄均<70岁,胸痛持续>1/2～<4小时,均无应用心得安的禁忌症。心得安组给药方法:首次剂量:体重<55公斤、5毫克;55～65公斤、6毫克;65～75公斤、7毫克;>75公斤、8毫克,静注5分钟以上,如正在服用β-阻滞剂,则心得安减少2毫克。其后,在试验开始后1、3、7、11、15、19、23、27小时各口服心得安40毫克,每次服药前测定心率和血压,如心率<50次/分,收缩压<100毫米汞柱,则停 This article reports the results of a prospective randomized controlled trial of propranolol to prevent ventricular fibrillation (VF) in patients with suspected acute myocardial infarction (AMI). Among the 735 patients, 364 patients were treated with propranolol and 371 controls. All patients were under 70 years of age with persistent chest pain> 1/2 ~ <4 hours. No contraindications to propofol were given. The first dose: weight <55 kg, 5 mg; 55 ~ 65 kg, 6 mg; 65 ~ 75 kg, 7 mg;> 75 kg, 8 mg, intravenous injection for more than 5 minutes, such as being taken β-blockers, the peace of mind to reduce the 2 mg. Thereafter, at the 1,3,7,11,15,19,23,27 hours after the start of the test, each oral propranolol 40mg, before each test of heart rate and blood pressure, such as heart rate <50 beats / min, systolic blood pressure < 100 mm Hg, then stop