目的探讨分析胆囊结石伴急性胰腺炎的患者行腹腔镜下胆囊切除术的时机。方法选择我科46例行腹腔镜胆囊切除术的患者,按手术时间不同分为早期组与延期组各23例,早期组在入院72小时内进行手术,延期组先行保守治疗,待病情稳定后再接受手术治疗,对比两组术中、术后康复情况。结果延期组术后住院时间、白细胞及血尿淀粉酶指标恢复正常时间显著短于早期组(P<0.05);术后半年,两组均无胰腺炎复发。结论胆囊结石合并急性胰腺炎患者先积极进行保守治疗,待病情稳定后再行手术,能够明显缩短患者术后恢复时间,促进患者术后康复。 Objective To investigate the timing of laparoscopic cholecystectomy in patients with gallstone and acute pancreatitis. Methods A total of 46 patients undergoing laparoscopic cholecystectomy in our department were divided into two groups according to different operation time: 23 cases in the early group and the deferred group, and the latter group undergoing surgery within 72 hours after admission. The patients in the deferred group were treated conservatively until the disease was stable Then surgery, compared two groups of intraoperative and postoperative recovery. Results Postoperative hospital stay, leukocyte and hematuria, amylase index in deferred group were significantly shorter than those in early group (P <0.05). No recurrence of pancreatitis occurred in both groups after 6 months. Conclusions Patients with gallstone and acute pancreatitis should be actively treated conservatively before operation after stable condition, which can significantly shorten the postoperative recovery time and promote postoperative recovery.