胞二磷胆碱为水溶性注射液[1] ,核苷衍生物 ,对治疗脑出血、脑梗死、脑外伤、脑萎缩及其后遗症有明显疗效。随着临床应用本药日益增多 ,其毒副作用逐渐显现出来 ,笔者 1998～ 2 0 0 1年遇到应用胞二磷胆碱后 ,出现精神异常者 2例 ,现报道如下 :1　病例介绍例 1:患者男 ,17岁 , Citicoline is a water-soluble injection [1], nucleoside derivatives, for the treatment of cerebral hemorrhage, cerebral infarction, traumatic brain injury, brain atrophy and its sequelae have a significant effect. With the clinical application of this drug is increasing, the toxic side effects gradually emerged, the author met with citicoline from 1998 to 2001, there are 2 cases of mental disorders, are reported as follows: 1 Case Introduction Example 1 : Patient male, 17 years old,