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以前报道了在仔鱼期口服异性激素后金鱼性分化朝两个方向完全反转的实验。遗传上的雌鱼性反转为雄鱼是用甲基睾丸酮诱导的,而遗体上的雄鱼性反转为雌鱼则是由雌酮诱导的。通过性转化的动物与正常动物交配获得性机能反转的成功,为性别决定的同型—异型配子机制提供了确凿的证据。如果雌鱼配子是异型(ZW)而雄鱼配子是同型(ZZ),假定1尾雄鱼(ZZ)转变为雌鱼与正常的雄鱼(ZZ)交配,可以获得全雄子代。另一方面,如果雄鱼配子是异型(XY)而雌鱼配子是同型(XX),假定1尾雄鱼(XY)转变为雌鱼与正常雄鱼(XY)交配,其子代的基因型的比例是1 XX:2XY:1 YY或1♀:3,如果YY基因型的合子发育成有存活力的雄鱼的话。
Previously reported the goldfish sexual differentiation in the larvae after oral heterosexual inversions completely reversed in both directions of the experiment. Genetically female sex reversal of males is induced by methyltestosterone, while males revert to males induced by estrone. The success of sexual function reversal through mating of sexually-transformed animals with normal animals provides conclusive evidence for the sex-isomorphic gametogenesis mechanism. If female gametes are zygotic (ZW) and male gametes are homozygous (ZZ), the whole male progeny can be obtained assuming that one male (ZZ) is converted to a female and the other male (ZZ) mates. If, on the other hand, male gametes are allomorphic (XY) and female gametes are isotype (XX), assuming that one male (XY) is transformed into a female mating with a normal male (XY), the offspring’s genotype The ratio is 1 XX: 2XY: 1 YY or 1♀: 3 if the zygote of the YY genotype develops into a viable males.