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目的探讨弥散加权成像(DWI)联合磁共振动态增强扫描(DCE-MRI)在肝脏局灶性结节性病变的检出与鉴别诊断中的价值。方法回顾性分析140例肝脏局灶性结节性病变患者行DWI并联合DCE-MRI的图像特点。结果原发性肝癌ADC值为(0.72±0.53)×10~(-3) mm~2/s,肝转移瘤ADC值为(0.97±0.62)×10~(-3) mm~2/s,肝血管瘤ADC值为(1.94±0.38)×10~(-3) mm~2/s,肝囊肿ADC值为(2.54±0.67)×10~(-3) mm~2/s。肝血管瘤的ADC值远高于原发性肝癌和肝转移瘤,差异具有统计学意义(P<0.05)。DWI联合DCE-MRI病灶的检出率和诊断符合率分别提升到100%、98%。结论 DWI联合DCE-MRI可提高肝脏局灶性结节性病变的检出率和诊断符合率,能比较准确的判断肝脏占位病变的性质,具有重要的临床诊断价值。
Objective To investigate the value of diffusion weighted imaging (DWI) combined with dynamic contrast-enhanced magnetic resonance (DCE-MRI) in the detection and differential diagnosis of focal nodular lesions in the liver. Methods We retrospectively analyzed the features of DWI combined with DCE-MRI in 140 patients with focal focal nodular lesions. Results The ADC value of primary liver cancer was (0.72 ± 0.53) × 10 ~ (-3) mm ~ 2 / s and that of liver metastases was (0.97 ± 0.62) × 10 ~ (-3) mm ~ 2 / The ADC value of hepatic hemangioma was (1.94 ± 0.38) × 10 ~ (-3) mm ~ 2 / s and the hepatic cyst was (2.54 ± 0.67) × 10 ~ (-3) mm ~ 2 / s. The ADC value of hepatic hemangiomas was much higher than that of primary liver cancer and liver metastases, the difference was statistically significant (P <0.05). The detection rate and diagnostic coincidence rate of DWI and DCE-MRI lesions were increased to 100% and 98% respectively. Conclusion DWI combined with DCE-MRI can improve the detection rate and diagnostic coincidence rate of focal nodular lesions in liver, and can accurately determine the characteristics of hepatic lesions, which has important clinical diagnostic value.