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目的研究丙酸氯倍他索乳膏家兔体内药代动力学特性。方法采用高效液相色谱法。结果单次给药后2h左右达峰，经多次给药后家兔体内的血药峰浓度及谷浓度呈上升趋势。结论显示丙酸氯倍他索在家兔体中有蓄积作用。
Objective To study the pharmacokinetics of clobetasol propionate cream in rabbits. Methods Using high performance liquid chromatography. The results peaked about 2h after a single administration, after repeated administration of rabbit blood peak concentration and trough concentrations showed an upward trend. Conclusions show that clobetasol propionate has an accumulation effect in rabbits.