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神经管畸形是中枢神经系统发育过程中因神经管闭合不全所造成的一组严重出生缺陷,主要包括无脑儿、脑膨出及脊柱裂,大约占全部出生缺陷的1/3。我国是世界上神经管畸形的高发国,每年至少有8万至10万病例发生,是造成孕妇流产、围产儿和婴儿死亡以及患者终身残疾的主要原因之一。我市神经管畸形的发生率分别为:95年1.25％,96年1.0％。97年0.75％。此病关键在于预防,我院自1998年3月至1999年4月给计划生育的妇女服用国产的斯利安预防神管畸形,取得了较好的效果,现报道如下。
Neural tube deformity is a group of serious birth defects caused by neural tube insufficiency during the development of the central nervous system, including anencephaly, encephalocele and spina bifida, accounting for about 1/3 of all birth defects. As the highest incidence of neural tube defects in the world, China has at least 80,000 to 100,000 cases of miscarriage each year. It is one of the major causes of miscarriage in pregnant women, perinatal and infant deaths and life-long disability in patients. The incidence of neural tube defects in our city were: 1.25% in 1995 and 1.0% in 1996. 0.75% in 1997. The key lies in the prevention of disease, our hospital from March 1998 to April 1999 to family planning women take domestic Sliean prevention of neural tube defects, and achieved good results, are reported below.