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感染是急性白血病患者死亡的常见原因,其早期诊断尤为困难,因易被中性白细胞减少所掩盖,而细菌培养一般需要24小时以上。虽已报导了一些快速诊断方法,但都不太可靠。本文利用感染时的一些急性蛋白反应作过筛试验,即定量检测血清中C-反应性蛋白(简作C-RP)、α_1-抗胰蛋白酶和血酸类粘蛋白(α-酸性糖蛋白)。将38例白血病患者(20例急粒、5例慢粒、6例急淋及7例慢淋)选作研究对像。其中17例临床有感染证据,但细菌培养未证实(7例肺部感染、10例蜂窝组织炎或/及组织坏死)
Infection is a common cause of death in patients with acute leukemia, which is particularly difficult to diagnose early because it is easily obscured by neutropenia, whereas bacterial culture generally takes more than 24 hours. Although some rapid diagnostic methods have been reported, they are not reliable. In this paper, a number of acute reactions when the protein reaction screening test, the quantitative detection of serum C-reactive protein (C-RP for short), α 1-antitrypsin and blood mucin (α-acid glycoprotein) . Thirty-eight patients with leukemia (20 acute, 5 slow, 6 acute and 7 chronic) were selected as study subjects. Of these, 17 had clinical evidence of infection, but bacterial culture was not confirmed (7 with pulmonary infection, 10 with cellulitis and / or tissue necrosis)