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目的及时了解广东省流行性脑脊髓膜炎(流脑)流行及菌群变化情况,预测发病趋势,为制订与调整预防流脑的策略与措施提供科学依据。方法采用描述流行病学方法。结果广东省2005年共报告流脑105例,发病高峰在2～4月,发病年龄以青壮年为主,发病人群主要为民工或外来打工者,与前5年相比发病年龄高峰后移。健康人群中A群脑膜炎奈瑟菌(Nm)IgG抗体阳性率为78.9%,C群NmIgG抗体阳性率为23.7%,健康人群总带菌率为0.65%。结论将Nm多糖疫苗纳入国家儿童免疫规划管理,流行期间加强对外来流动人口的管理,通过督导等一系列综合措施,提高预防效果及时控制疫情。
Objective To keep abreast of epidemic cerebrospinal meningitis (MC) prevalence in Guangdong Province and changes in flora, to predict the trend of the disease, and to provide a scientific basis for the formulation and adjustment of strategies and measures to prevent ECM. Methods used to describe epidemiological methods. Results In 2005, 105 cases of meningococcal disease were reported in Guangdong Province. The peak incidence peak was between February and April. The age of onset was mainly young and middle-aged. The main incidence was migrant workers or migrant workers. The peak age of onset was postponed compared with the previous 5 years. In healthy population, the positive rate of Neisseria meningitides serogroup A (Nm) was 78.9%, that of C group NmIgG was 23.7%, and that of healthy population was 0.65%. Conclusion The Nm polysaccharide vaccine was included in the management of national childhood immunization programs. During the epidemic, the management of floating population was strengthened. Through a series of comprehensive measures such as supervision, the Nm polysaccharide vaccine was used to improve the prevention effect and control the outbreak in time.