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目的分析糖尿病(DM)患者增殖期糖尿病视网膜病变(PDR)发生的影响因素及其管理。方法回顾性分析天全县人民医院2014年6月—2015年6月收治的DM患者127例,根据患者有无并发PDR分为对照组(n=62)和PDR组(n=65)。记录患者的性别、用药种类、体质量、年龄、运动、饮食控制、DM病程与其他并发症、糖化血红蛋白、血脂、空腹血糖、血压,采用多因素Logistic回归分析DM患者PDR发生的影响因素。结果两组患者性别、年龄、体质量、血脂比较,差异无统计学意义(P>0.05);PDR组患者DM病程、运动、饮食控制、用药种类、其他并发症、空腹血糖、糖化血红蛋白及血压情况与对照组比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,DM病程、运动、饮食控制、用药种类、其他并发症、空腹血糖、糖化血红蛋白及血压是DM患者PDR发生的独立危险因素(P<0.05)。结论 DM病程、运动、饮食控制、用药种类、其他并发症、空腹血糖、糖化血红蛋白及血压是DM患者PDR发生的独立危险因素。
Objective To analyze the influencing factors and management of proliferative diabetic retinopathy (PDR) in patients with diabetes mellitus (DM). Methods A retrospective analysis of 127 patients with DM in Tianquan County People’s Hospital from June 2014 to June 2015 was divided into control group (n = 62) and PDR group (n = 65) according to whether patients had concurrent PDR. The factors such as sex, type of medication, body weight, age, exercise, diet control, course of DM and other complications, glycosylated hemoglobin, blood fat, fasting blood glucose and blood pressure were recorded and the influencing factors of PDR in DM patients were analyzed by multivariate Logistic regression. Results There was no significant difference in gender, age, body weight and blood lipids between the two groups (P> 0.05). The duration of diabetes, exercise, diet control, medication type, other complications, fasting blood glucose, glycosylated hemoglobin and blood pressure Compared with the control group, the difference was statistically significant (P <0.05). Multivariate logistic regression analysis showed that DM duration, exercise, diet control, medication type, other complications, fasting blood glucose, glycosylated hemoglobin and blood pressure were independent risk factors for PDR in DM patients (P <0.05). Conclusion DM course of disease, exercise, diet control, medication type, other complications, fasting blood glucose, glycosylated hemoglobin and blood pressure are independent risk factors of PDR in DM patients.