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目的探讨内镜下cN0期甲状腺乳头状癌手术的可行性及有效性。方法回顾性分析浙江大学医学院附属第二医院2010年4月至2011年7月间收治的20～50岁间女性cN0期甲状腺乳头状癌164例病人资料。分为两组,其中行开放手术组105例,内镜手术组59例。对两组病人的并发症和清扫淋巴结个数等资料进行统计学分析。结果两组病人术后出现声音嘶哑、饮水呛咳和低钙血症等并发症的发生率相比差异无统计学意义(P>0.05);内镜手术组清扫淋巴结273枚,平均4.6枚,开放手术组清扫淋巴结605枚,平均5.8枚,两组差异无统计学意义(P>0.05)。术后随访12～28个月,平均随访19个月,无复发病例。结论内镜下cN0期甲状腺乳头状癌的手术治疗是安全可行的,可兼顾疗效和美容。
Objective To investigate the feasibility and effectiveness of endoscopic cN0 thyroid papillary carcinoma surgery. Methods A retrospective analysis of 164 cases of thyroid papillary carcinoma in women aged 20-50 years from April 2010 to July 2011 in the Second Affiliated Hospital of Zhejiang University School of Medicine was performed. Divided into two groups, including open surgery group of 105 cases, 59 cases of endoscopic surgery group. The comparisons of the two groups of patients and the number of lymph nodes were statistically analyzed. Results There was no significant difference between the two groups in the incidence of hoarseness, complication of cough of drinking water and hypocalcemia (P> 0.05). There were 273 lymph nodes in the endoscopic surgery group with an average of 4.6, There were 605 clear lymph nodes in the open surgery group, with an average of 5.8 pieces. There was no significant difference between the two groups (P> 0.05). The patients were followed up for 12-28 months, with a mean follow-up of 19 months without recurrence. Conclusion Endoscopic cN0 thyroid papillary carcinoma of the surgical treatment is safe and feasible, both efficacy and beauty.