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目的分析糖化血红蛋白(HbAlc)在空腹血糖正常的妊娠糖尿病孕妇中的临床应用价值。方法选择2008年12月-2010年12月来我院门诊及住院的468例孕妇作为研究对象,其中正常孕妇(NGT)312例,糖耐量受损(GIGT)孕妇80例,空腹血糖正常的妊娠糖尿病孕妇(GDM)76例,分别称为NGT组、GIGT组和GDM组,对三组孕妇均进行HbAlc检测、口服糖耐量实验(OGTT)、空腹血糖(FPG)监测,对比分析三组孕妇的HbAlc、OGTT、FPG。结果 GDM组的HbAlc、OGTT明显高于GIGT组和GDM组,差异均具有统计学意义(P<0.05)。结论 HbAlc检测可作为空腹血糖正常的GDM孕妇的筛查指标之一,可以提高GDM的诊断率,简化其诊断流程,值得临床推广应用。
Objective To analyze the clinical value of glycosylated hemoglobin (HbA1c) in pregnant women with gestational diabetes mellitus with normal fasting plasma glucose. Methods A total of 468 pregnant women from our hospital from December 2008 to December 2010 were enrolled in this study. Among them, 312 were normal pregnant women (NGT), 80 were pregnant women with impaired glucose tolerance (GIGT), 80 were pregnant with fasting plasma glucose 76 pregnant women with diabetes mellitus (GDM) were respectively referred to as NGT group, GIGT group and GDM group. HbAlc, oral glucose tolerance test (OGTT) and fasting plasma glucose (FPG) were monitored in all three groups of pregnant women. HbAlc, OGTT, FPG. Results The levels of HbAlc and OGTT in GDM group were significantly higher than those in GIGT group and GDM group (P <0.05). Conclusion HbA1c test can be used as a screening index for pregnant women with normal fasting plasma glucose, which can improve the diagnostic rate of GDM and simplify its diagnostic procedure, which is worthy of clinical application.