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目的:探讨儿童过敏性结膜炎与变应性鼻炎的相关性研究及鼻眼联合防治的临床效果。方法:回顾性分析300例儿童过敏性结膜炎与310例儿童变应性鼻炎患者的临床资料,对儿童过敏性结膜炎与变应性鼻炎的相关性进行分析后将所有患儿随机均分为对照组与观察组,对照组采用常规点眼的方法进行治疗,观察组则采用鼻朗喷鼻联合人工泪液点眼进行治疗。比较两组临床疗效及不良反应情况。结果:(1)300例过敏性结膜炎患儿中,50例(16.67%)并发变应性鼻炎;310例变应性鼻炎患儿中,59例(19.03%)并发过敏性结膜炎(P>0.05);(2)109例同时并发两种疾病患儿中,均进行眼结膜与鼻粘膜的刮片检查嗜酸性粒细胞,其中60例(55.05%)结膜刮片与67例(61.47%)鼻粘膜刮片检测到嗜酸性粒细胞(P>0.05);(3)两组治疗前后BUT及角膜荧光素染色评分、症状评分、临床总有效率比较差异明显(P<0.05)。结论:儿童过敏性结膜炎与变应性鼻炎具有一定的相关性;鼻朗喷鼻联合人工泪液点眼治疗儿童合并变应性鼻炎的临床疗效显著。
Objective: To investigate the correlation between allergic conjunctivitis and allergic rhinitis in children and the clinical effect of combined prevention and treatment of nasal and eye. Methods: A retrospective analysis of 300 cases of children with allergic conjunctivitis and 310 cases of children with allergic rhinitis in patients with clinical data on children with allergic conjunctivitis and allergic rhinitis after the analysis of all children were randomly divided into The control group and the observation group and the control group were treated with the conventional eye-spotting method. The observation group was treated with nasolabial nasal spray combined with artificial tear ophthalmoscopy. The clinical efficacy and adverse reactions of the two groups were compared. Results: (1) Of the 300 children with allergic conjunctivitis, 50 (16.67%) had allergic rhinitis. Of the 310 children with allergic rhinitis, 59 (19.03%) had allergic conjunctivitis (P > 0.05). (2) In 109 children with both concurrent diseases, eyelid eyelid was detected by conjunctival and nasal mucosal smear. Among them, 60 (55.05%) conjunctival smears and 67 (61.47% (P> 0.05); (3) The BUT and corneal fluorescein staining scores, symptom scores and total clinical effective rate were significantly different between the two groups before and after treatment (P <0.05). Conclusion: Allergic conjunctivitis in children has some correlation with allergic rhinitis; rhinoplasty and rhinoplasty combined with artificial tears in the treatment of children with allergic rhinitis have significant clinical curative effect.