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目的评价米索前列醇联合催产素预防剖宫产术后出血的临床疗效。方法选择2012年1月至2013年1月在我院进行剖宫产手术的98例产妇作为观察对象,随机其分成两组,治疗组在剖宫产术后应用米索前列醇联合催产素预防产后出血,对照组单纯应用催产素预防产后出血,比较两组产妇术中、术后2h、24h的出血量,同时比较两组产妇产后出血发生率及不良反应发生率。结果治疗组术中、术后2h、24h出血量明显低于对照组,差异有统计学意义(P<0.01);治疗组产后无1例出血,对照组产后出血3例,对照组产后出血发生率明显高于对照组,差异有统计学意义(P<0.01);两组患者均无明显不良反应发生。结论米索前列醇联合催产素可明显减少剖宫产术后出血以及出血发生率,且无不良反应发生。
Objective To evaluate the clinical efficacy of misoprostol combined with oxytocin in preventing bleeding after cesarean section. Methods 98 maternal women undergoing cesarean section in our hospital from January 2012 to January 2013 were randomly divided into two groups. The treatment group was treated with misoprostol combined with oxytocin Postpartum hemorrhage, the control group simply the application of oxytocin to prevent postpartum hemorrhage, the two groups of maternal intraoperative and postoperative bleeding 2h, 24h, at the same time, the incidence of postpartum hemorrhage and adverse reactions in both groups were compared. Results The intraoperative and postoperative 2h, 24h hemorrhage volume in the treatment group was significantly lower than that in the control group, the difference was statistically significant (P <0.01); no bleeding occurred in the treatment group postpartum, 3 cases of postpartum hemorrhage in the control group and postpartum hemorrhage in the control group The rate was significantly higher than the control group, the difference was statistically significant (P <0.01); no adverse reactions occurred in both groups. Conclusion Misoprostol combined with oxytocin can significantly reduce the incidence of bleeding and bleeding after cesarean section, and no adverse reactions occurred.