1986年上半年新罕布什尔州某市有4例乙型肝炎临床病例报告,每例均经血清学证实.4例病人都曾看过同一口腔医师,并在发病前3～5个月拔过牙,其中三例曾一次拔牙数只.4例病人都否认接触过乙型肝炎病毒感染的其他危险因素。 4例中有一例HBsAg血清阳性持续6个月以上而成为慢性乙型肝炎携带者,其HBsAg亚型与那位口腔医师一样为ad。86年上半年该市的其它十例乙肝病人,两例为静脉使用毒品 Four cases of hepatitis B clinical cases were reported in a city of New Hampshire in the first half of 1986. Each case was confirmed by serology. All 4 patients had seen the same dentist and pulled their teeth 3 to 5 months before onset, Three of the patients once extracted only one number of teeth, and all four patients denied exposure to other risk factors for hepatitis B virus infection. One out of 4 cases was positive for HBsAg seropositivity for 6 months or more and became a chronic hepatitis B carrier. The HBsAg subtype was the same as that of the dentist. In the first half of 1986, ten other hepatitis B patients were in the city and two were used intravenously