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目的探讨青年人大肠癌临床病理及预后特点。方法分析88例青年人大肠癌的临床、内镜、病理、预后情况并与同期483例中老年人比较。结果两组粘液血便、排便习惯异常、高分化腺癌、粘液腺癌、未分化癌、DukesB1期、DukesD期和根治性切除率比较,差异有显著意义(P<0.05)。结论青年人大肠癌分化较差但根治性切除率高,5年生存率与中老年人相近。
Objective To investigate the clinicopathological characteristics and prognosis of colorectal cancer in young people. Methods The clinical, endoscopic, pathological and prognosis of 88 young patients with colorectal cancer were analyzed and compared with 483 middle-aged and elderly patients in the same period. Results There were significant differences between mucosal bloody stool, abnormal bowel habits, well-differentiated adenocarcinoma, mucinous adenocarcinoma, undifferentiated carcinoma, DukesB1 stage, DukesD stage and radical resection rate (P <0.05). Conclusion The colorectal cancer in young people is poorly differentiated but the radical resection rate is high. The 5-year survival rate is similar to that of middle-aged and elderly people.