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目的:评价职业场所高血压规范化管理对提高职业人群高血压合并糖尿病患者血压控制率的效果。方法:采用流行病学现场类试验的研究方法，在全国不同省份选取61个工作场所，在兼顾工作场所类型和规模的前提下，在不同省份分别选取2~4个经济水平及医疗条件相似的职业场所，选取其中1~3个作为干预组场所，另1家为对照组场所。最终纳入443例高血压合并糖尿病的患者，干预组场所中共347例为干预组，对照组场所中96例为对照组。医生经培训后对干预组患者进行为期24个月的规范化管理工作，每月1次定期随访，记录血压、危险因素和靶器官损害变化及治疗情况；对照组无特殊干预，仅收集基线和24个月的相关信息。比较2组患者血压值、血压控制率和血糖变化情况。结果:经高血压规范化管理后，干预组的高血压控制率从24.2%上升到了63.7%（n P<0.05），收缩压和舒张压较管理前平均下降10.2（11.9~8.4） mmHg（1 mmHg=0.133 kPa）和7.7（8.8~6.6）mmHg，管理前后差异均有统计学意义（n P<0.05），且血糖也有小幅度下降（n P<0.001）。血压控制率干预组(63.7%)高于对照组（46.9%）（n P<0.05）。对照组收缩压和舒张压较管理前平均下降5.6（8.9~2.2） mmHg和4.5（6.6~2.4） mmHg（n P<0.05）。n 结论:基于职业场所的高血压规范化管理有效降低了职业人群中高血压合并糖尿病患者的整体血压水平，提高了高血压控制率。“,”Objective:To evaluate the effects of standardized management of hypertension on blood pressure control of hypertension patients with diabetes mellitus in workplace population.Methods:Taking the type and size of workplace into consideration, 61 work sites were selected in different provinces by using epidemiological field trial method. In each selected province, 2-4 work sites with similar economic and medical conditions were chosen, among which 1-3 were designated as the intervention group and the other one as the control group. In total, 443 patients with hypertension and diabetes mellitus were included, with 347 patients in the intervention group and 96 patients in the control group. After training, doctors conducted standardized management for patients in the intervention group for a period of 24 months, following up with them regularly once a month, and recorded changes in blood pressure, risk factors, target organ damage, and treatment, while the control group had no special intervention, and relevant information was collected only at baseline and 24 months. Blood pressure, blood pressure control rate, and blood glucose changes were compared between the two groups.Results:After receiving standardized management of hypertension, the control rate of hypertension for patients with both hypertension and diabetes mellitus in the intervention group increased from 24.2% to 63.7% (n P<0.05) and the participants’ blood pressure also significantly decreased, by 10.2 (11.9-8.4) mmHg (1 mmHg=0.133 kPa) for systolic blood pressure and 7.7 (8.8-6.6) mmHg for diastolic blood pressure (n P<0.05); moreover, the blood glucose also decreased slightly (n P<0.001). In addition, the control rate of blood pressure increased to 63.7% with the increase of management time. In the control group, the control rate of hypertension increased to 46.9% (n P<0.05) and the systolic and diastolic blood pressure decreased by 5.6 (8.9-2.2) and 4.5 (6.6-2.4) mmHg (n P<0.05).n Conclusions:The standardized management of hypertension in the workplace can effectively reduce overall blood pressure levels and improve the control rate of hypertension in the working population.