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前列腺素E_1(PGE_1)临床应用报道较少,我院用PGE_1治疗心功能不全,同时进行心脏收缩时间间期(STI)和超声心动图(UCG)检查,以观察PGE_1治疗心功能不全患者的急性效应和副作用。临床资料一、病例本组观察11例,男性4例,女性7例,年龄29～70岁,平均年龄46岁。其中冠心病3例,高心病1例,风心病4例,肺心病2例,心肌病1例,所有病例均有不同程度的全心或左心功能不全的临床表现。二、用药方法取PGE_1600μg稀释于5%葡萄糖溶液250毫升中,以每分钟15～20滴静脉点
Prostaglandin E_1 (PGE_1) has rarely been reported in clinic. PGE_1 was used in our hospital to treat cardiac insufficiency. Simultaneous systolic and diastolic time (STI) and echocardiography (UCG) were performed to observe the acuteness of PGE_1 in patients with cardiac insufficiency Effects and side effects. Clinical data First, the case observed in this group 11 cases, 4 males and 7 females, aged 29 to 70 years, mean age 46 years. There were 3 cases of coronary heart disease, 1 case of high heart disease, 4 cases of rheumatic heart disease, 2 cases of pulmonary heart disease and 1 case of cardiomyopathy. All cases had clinical manifestations of varying degrees of heart failure or left ventricular dysfunction. Second, medication PGE_1600μg diluted in 250ml of 5% glucose solution to 15 to 20 drops per minute intravenous point