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目的观察亚低温护理干预对失血性休克患者血清炎性因子及预后的改善作用。方法选择2015年1—10月该院收治的创伤失血性休克患者80例,随机分为观察组与对照组各40例。两组均予常规抗休克及限制性液体复苏治疗,对照组予常规护理,观察组联合应用亚低温护理干预。比较两组氧化应激反应、血清炎性因子及预后情况。结果治疗后观察组血清肿瘤坏死因子-α、白细胞介素-6、丙二醛含量、并发症发生率、病死率均明显低于对照组,白细胞介素-10、超氧化物歧化酶活性明显高于对照组,差异均有统计学意义(P<0.05)。结论亚低温护理干预可缓解创伤失血性休克患者炎症状态,减轻再灌注损伤,减少并发症,改善患者预后。
Objective To observe the effects of mild hypothermia nursing intervention on serum inflammatory factors and prognosis in patients with hemorrhagic shock. Methods Eighty patients with traumatic hemorrhagic shock who were admitted to our hospital from January to October in 2015 were randomly divided into observation group (40 cases) and control group (40 cases). Both groups were given conventional anti-shock and fluid resuscitation therapy, the control group were given routine care, the observation group combined with mild hypothermia nursing intervention. Oxidative stress, serum inflammatory factors and prognosis were compared between the two groups. Results After treatment, the levels of tumor necrosis factor-α, interleukin-6, malondialdehyde, morbidity and mortality in the observation group were significantly lower than those in the control group, and the activity of superoxide dismutase Higher than the control group, the difference was statistically significant (P <0.05). Conclusion Mild hypothermia nursing intervention can relieve the inflammatory state of traumatic hemorrhagic shock, reduce the reperfusion injury, reduce the complications and improve the prognosis of patients.