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本文根据我科２０多年来对颏下及颌下区肿瘤的术前临床诊断和术后病理诊断资料进行回顾时发现５例鼻咽癌以颏下及颌下三角区淋巴结转移为首发症状而误诊．作者认为鼻咽癌可以在颈部某些特定区域淋巴结转移为初发症状，但以颏下及颌下三角区淋巴结转移为首发症状者则极为罕见，单纯用经典的血行性转移、淋巴道转移和播散性转移的机理来解释是很困难的，但是用肿瘤生物化学和分子生物学的观点来分析肿瘤的转移与嗜器官转移的一些生物大分子有关．据以本文对鼻咽癌以颏下及颌下三角区淋巴结转移为首发症状的病例加以报道和分析．
Based on our 20 years of clinical diagnosis of submental and submandibular tumors of the tumor and pathological diagnosis of retrospective study found that 5 cases of nasopharyngeal carcinoma with submental and submandibular triangular lymph node metastasis as the first symptom of misdiagnosis . The authors believe that nasopharyngeal carcinoma can be lymph node metastasis in some areas of the neck as the initial symptoms, but to the submental and submandibular triangular lymph node metastasis as the first symptom is extremely rare, simply with the classic hematogenous metastasis, lymphatic metastasis And disseminated metastasis mechanism to explain it is very difficult, but from the perspective of tumor biochemistry and molecular biology to analyze the transfer of tumor associated with some biological macromolecules of organ metastasis. According to this article, nasopharyngeal carcinoma with submental and submandibular triangular lymph node metastasis as the first symptom of the cases were reported and analyzed.