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目的：探讨Ａ型肉毒毒素对面肌痉挛的远期疗效及副作用。方法：对１２２例面肌痉挛病人进行面部多点注射Ａ型肉毒毒素，对其疗效进行书信、电话或门诊随访。结果：Ａ型肉毒毒素治疗的总有效率为９６．０９％ （１７２／１７９），副作用主要为短期上睑下垂、患侧眼流泪，复视；重复注射不能延长面肌痉挛的复发时间；其疗效与病程长短和病情严重程度有关，病程越长，病情越重，有效时间越短。结论：Ａ型肉毒毒素对面肌痉挛是一种有效的治疗手段，但作用有限，反复注射不能控制其复发；病情越轻、治疗时间越早，疗效持续时间越长。
Objective: To investigate the long-term curative effect and side effects of botulinum toxin type A on hemifacial spasm. Methods: A total of 122 patients with hemifacial spasm were injected multi-point facial botulinum toxin type A, whose efficacy was reported by letter, telephone or outpatient follow-up. Results: The total effective rate of botulinum toxin type A treatment was 96.09% (172/179). The side effects were mainly short-term ptosis, ipsilateral eye tears and diplopia. Repeated injection could not prolong the recurrence time of hemifacial spasm. The efficacy and duration of the disease and the severity of the disease, the longer the duration of the disease, the more effective, the shorter the effective time. Conclusion: botulinum toxin type A is an effective treatment for hemifacial spasm, but its effect is limited. Repeated injections can not control recurrence. The lower the severity of the disease, the sooner the treatment is taken, the longer the curative effect is.