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流行性出血热(EHF)亦称肾综合征出血热(HFRS),由鼠类传播,野鼠型EHF 的病死率高(5～10％,高者可达30％以上),对人民健康,国民经济建设,工农业生产是一种直接威胁,并对我国的对外开放、旅游事业及外贸事业的发展有重要影响。HFRS 的病原是布尼亚病毒科(Buny-aviridac)中的汉坦病毒属(Hantavirus)有多种抗原性不同的血清型。其中1、2型病毒是 EHF 的病原,1型(Hantaan 病毒)由黑线姬鼠传播,是野鼠型 EHF 的病原,2型(Seoul 病毒)由褐家鼠和实验用大白鼠传播,是家鼠型和实验动物型 EHF 的病原,3型(Puumala 病毒)由欧洲棕背(鼠平)传播,是
Epidemic hemorrhagic fever (EHF), also known as hemorrhagic fever with renal syndrome (HFRS), is transmitted by mice and has a high mortality rate (5 to 10%, whichever is higher, up to 30%) in wild-type EHF. Economic construction, industrial and agricultural production are a direct threat and have a significant impact on the opening up of our country, the development of tourism and foreign trade in our country. The pathogen of HFRS is that there are several antigenically different serotypes in the Hantavirus in the Bunyaviridae family. Among them, type 1 and 2 viruses are the etiological agents of EHF. Type 1 (Hantaan virus) is transmitted by Apodemus agrarius and is the etiologic agent of echovirus of the wild type. Type 2 (Seoul virus) is transmitted by Rattus norvegicus and experimental rats The pathogen of murine and experimental animal EHF, type 3 (Puumala virus) is transmitted from European brown back (rat placenta) and is