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目的探讨LEEP锥切术在宫颈癌前期病变宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)的应用效果,为控制宫颈癌发生提供科学依据。方法回顾性分析本院实施LEEP宫颈锥切术治疗91例CINⅡ以上患者的临床资料,随访一年后观察组织病理变化及术后复发的情况。结果 91例CINⅡ以上患者锥切后,59例(64.8%)病理未进展,13例(14.28%)病理降级,4例(4.4%)阴性,15例(16.48%)升级;随之15例升级患者继续实施手术治疗,其中14例行全子宫切除,1例行宫颈癌根治术,随访满1年后,未见复发。76例锥切为最终治疗,随访观察1年后仅2例(2.63%)再次出现宫颈病变。结论 LEEP刀宫颈锥切术能准确诊断宫颈病变并能较有效治疗CIN,但锥切术后应密切随访。
Objective To investigate the application effect of LEEP conization in cervical intraepithelial neoplasia (CIN) and provide a scientific basis for controlling the occurrence of cervical cancer. Methods The clinical data of 91 patients with CINⅡcases treated with LEEP cervical conization were retrospectively analyzed. One year after follow-up, histopathological changes and postoperative recurrence were observed. Results The pathological changes of 59 cases (64.8%) of 91 patients with CINⅡ or above were not progressing. Thirteen patients (14.28%) were pathologically degraded, 4 patients (4.4%) were negative and 15 patients (16.48%) were escalated. Patients continued to undergo surgery, including 14 cases of hysterectomy, 1 case of cervical cancer radical surgery, follow-up after 1 year, no recurrence. 76 cases of conization for the final treatment, 1 year follow-up observation after only 2 cases (2.63%) cervical lesions again. Conclusion LEEP knife cervical conization can accurately diagnose cervical lesions and more effective treatment of CIN, but the cone should be followed up closely.