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本文分析111例良恶性胃病的血和胃液CEA测定结果(其中88例同时检测血和胃液CEA),与胃镜检查和活检病理特点相比较。胃液CEA值高于血CEA(约高1.5～15倍),45例恶性胃病中,胃液CEA阳性41例,仅1例单独血CEA阳性。胃液CEA对恶性胃病的诊断具有一定的特异性,癌和HR(高危险人)组的阳性率分别为88.57％(31/35例)和82.35％(14/18例),与良性胃病相比有显著差异(P<0.01)。胃液CEA测定是一个简便、安全、具有一定特异性和敏感性筛诊胃癌的方法。作者建议可以用于健康人或RH人群的一项普查方法,对CEA增高患者,进一步深入检查。
In this paper, 111 cases of benign and malignant gastropathy were analyzed by CEA in blood and gastric juice (88 of them were simultaneously tested for CEA in blood and gastric juice), and compared with gastroscopy and biopsy pathological features. The CEA value in gastric juice was higher than that in blood CEA (about 1.5 to 15 times higher). In 45 cases of malignant stomach disease, 41 cases were CEA positive in gastric juice, and only 1 case was CEA positive in blood alone. Gastric juice CEA has a certain specificity for the diagnosis of malignant gastropathy. The positive rates of cancer and HR (high risk group) were 88.57% (31/35 cases) and 82.35% (14/18 cases), respectively, compared with benign gastropathy. There was a significant difference (P<0.01). CEA measurement in gastric juice is a simple, safe, specific and sensitive method for the diagnosis of gastric cancer. The authors suggest a census method that can be used for healthy people or RH populations to further examine patients with higher CEA.