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20例年龄、体重指数相似的特发性多毛妇女随机接受安体舒通100mg/天或氟它胺250mg,每日二次共9月,比较其疗效,受试前均查血象、肝、肾功能,并做全面的内科、妇科及内分泌检查,包括LH、FSH、睾酮(T)、去氢表雄酮硫酸盐(Ds)。多毛评分据Ferriman-Gallway标准,受试前及服药后3、6、9月重复评分。 结果:所有患者多毛症状均得到改善,服药后3、6、9月多毛评分安体舒通组分别降低20.9％、32.9％及39.6％,而氟它胺组则降低26.4％、39.5％
Twenty patients with idiopathic hirsutism who were similar in age and body mass index were randomized to receive either spironolactone 100 mg / day or flutamide 250 mg twice a day for 9 months. Function, and to do a comprehensive medical, gynecological and endocrine tests, including LH, FSH, testosterone (T), dehydroepiandrosterone sulfate (Ds). Hirsute score according to Ferriman-Gallway standards, before and after taking the test 3, 6, September repeat score. Results: The hirsutism symptoms of all patients were improved. After 3, 6, and 9 months of treatment, the hairiness score of spironolactone group decreased by 20.9%, 32.9% and 39.6% respectively, while that of flutamide group decreased by 26.4% and 39.5%