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７５ｍＧｙＸ射线全身照射后下丘脑５羟色胺（５－ＨＴ）含量升高，血清ＡＣＴＨ和皮质酮（ＣＳ）水平降低，伴有胸腺和牌细胞免疫功能增强．下丘脑内注入５－ＨＴ引起血清ＡＣＴＨ下降的同时，导致胸腺和牌细胞免疫反应性上升．作者认为，低剂量辐射引起植物神经中枢５－ＨＴ能性神经元兴奋，使下丘脑内５－ＨＴ增多，同时垂体分泌ＡＣＴＨ减少，导致肾上腺皮质功能下调，部分解除下丘脑－垂体－肾上腺皮质系统对免疫器官的张力性抑制，从而诱发免疫功能增强。这是分析低剂量辐射兴奋效应的机制时应当考虑的一个重要因素．
After 75mGy X-ray, the content of 5-HT in the hypothalamus increased, the levels of serum ACTH and corticosterone (CS) decreased, and the thymus and card cell immune function were enhanced. Hypothalamic injection of 5-HT causes serum ACTH decreased at the same time, leading to thymus and card cell immune response increased. The authors argue that low dose radiation causes excitement of 5-HT-capable neurons in the autonomic nerve center to increase 5-HT in the hypothalamus while decreasing ACTH secretion from the pituitary, leading to a decrease in adrenal cortical function and a partial release of the hypothalamic-pituitary-adrenal cortex system Tonic suppression of immune organs, thereby inducing immune function enhancement. This is an important factor to consider when analyzing the mechanism of low dose radiation excitability.