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目的观察胺碘酮治疗老年冠心病心律不齐的临床效果及价值。方法选取2013年6月-2014年9月医院治疗的老年冠心病心律不齐患者156例,按照入院的顺序分为观察者和对照组各78例。其中对照组给予常规的基础药物进行长期治疗,观察者给予胺碘酮长期维持治疗。观察2组的疗效及心律改善情况。结果观察组治疗后的总有效率92.31%明显高于对照组的78.20%(P<0.05)。观察组治疗期间不良反应发生率为3.85%明显低于对照组的15.38%,差异均有统计学意义(P<0.05)。结论老年冠心病心律不齐患者应用胺碘酮治疗,疗效显著,有较高的安全性,不良反应率低,值得临床推广应用。
Objective To observe the clinical effect and value of amiodarone on arrhythmia of elderly patients with coronary heart disease. Methods 156 cases of elderly patients with coronary heart disease and arrhythmia were selected from June 2013 to September 2014 in our hospital. According to the order of admission, the patients were divided into observation group and control group with 78 cases each. The control group was given routine basic drugs for long-term treatment, the observer was given amiodarone long-term maintenance treatment. The curative effect and improvement of heart rhythm in the two groups were observed. Results The total effective rate of the observation group after treatment was significantly higher than that of the control group (92.20% vs 78.20%, P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that of the control group (3.85% vs 15.38%, P <0.05). Conclusions The treatment of amiodarone in elderly patients with coronary heart disease with arrhythmia has significant curative effect, high safety and low adverse reaction rate, which deserves clinical application.