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营养和代谢与生殖健康关系密切。多种生殖系统疾病,包括多囊卵巢综合征、闭经、卵巢癌均与营养不良、糖尿病、肥胖有关。此外,禁食很多物种的食物可导致生殖功能下降,原因是未成熟的卵细胞(卵母细胞)的发育被阻止了。阐明营养物质如何在未成熟的卵母细胞中蓄积可有效地洞察代谢性疾病与生殖功能障碍间的关系。Allan Spradling和Matthew Sieber新的研究工作重点是卵母细胞发育过程中三酰甘油以及固醇类(类固醇的一类)的蓄积
Nutrition and metabolism and reproductive health are closely related. A variety of reproductive system diseases, including polycystic ovary syndrome, amenorrhea, ovarian cancer are associated with malnutrition, diabetes, obesity. In addition, fasting many species of food can result in a decline in reproductive function due to the fact that immature egg (oocyte) development is prevented. Clarifying how nutrients accumulate in immature oocytes can provide insight into the relationship between metabolic and reproductive dysfunctions. New research by Allan Spradling and Matthew Sieber focused on the accumulation of triglycerides and sterols (a class of steroids) during oocyte development