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目的探讨CT灌注对急性缺血性脑卒中(AIS)溶栓治疗后出血转化(HT)的评价性。方法选取56例于2015年5月-2017年2月接收的AIS患者,根据CT平扫图像出血与否分为出血组(n=20)和未出血组(n=36),每个病例均测患侧和健侧CTP参数,计算相对参数值。结果出血组患者r CBF值、r CBV值均显著低于未出血组(P<0.05),而两组r MTT比较均无明显差异性(P>0.05);r CBV、r CBF与HT均呈负相关性(P<0.05)。结论 CTP对称部位相对参数值对于AIS溶栓治疗HT的预测有重要意义。
Objective To investigate the evaluation of CT perfusion on hemorrhagic transformation (HT) after thrombolytic therapy of acute ischemic stroke (AIS). Methods Fifty-six patients with AIS who received from May 2015 to February 2017 were divided into hemorrhage group (n = 20) and non-hemorrhage group (n = 36) according to whether the CT images were hemorrhaged or not. Each case Measure the contralateral and contralateral CTP parameters and calculate the relative parameter values. Results The values of r CBF and r CBV in the bleeding group were significantly lower than those in the non-bleeding group (P <0.05), while there was no significant difference between the two groups (P> 0.05); r CBV, r CBF and HT were Negative correlation (P <0.05). Conclusion The relative parameters of CTP symmetry sites are of great significance for the prediction of HT by thrombolytic therapy with AIS.