Survivin是新近发现的凋亡抑制蛋白,具有抑制细胞凋亡和调节细胞分化的双重功能,其与肝癌的发生、发展及预后紧密相关。文章综述了近年Survivin在肝癌发生、发展、治疗及预后中的研究情况。 Survivin, a recently discovered inhibitor of apoptosis, has the dual function of inhibiting apoptosis and regulating cell differentiation, which is closely related to the occurrence, development and prognosis of hepatocellular carcinoma. The article summarizes the recent studies on the occurrence, development, treatment and prognosis of Survivin in hepatocellular carcinoma.