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我院自1986~1990年共收治22例结核性脑膜炎(结脑),选用含SHZ并氟美松方案,取得较为满意的效果。病人年龄1~56岁。脑膜炎型11例(50%),伴颅神经损害或颅内定位体征的脑膜脑炎型9例(40.9%),有脊髓损害的蛛网膜下腔梗阻的脑脊髓膜炎型2例;中晚期和迁延期占77.7%。合并肺结核20例,其中原发型3例、血播型16例、浸润型1例。治疗方案 SM0.75日1次肌注、INH0.3日顿服并静脉滴注0.6~0.9、PZA0.5日3次口服。儿童用量酌减;全部并用氟美松静脉滴注0.1~0.2mg/kg;3例曾椎管给药氟美松,10例曾加用RFP。文献报道,多采用去氢或氢化可的松,并主张1个月后开始减量,疗程不超过3个月。本组应用氟美松是在脑脊
Twenty-two patients with tuberculous meningitis (tuberculous meningitis) were treated in our hospital from 1986 to 1990, and SHZ and dexamethasone-containing regimens were selected to achieve satisfactory results. The patient is 1 to 56 years old. 11 cases (50%) of meningitis, 9 cases (40.9%) of meningoencephalitis with cranial nerve lesion or intracranial localization signs, 2 cases of spinal meningitis with spinal cord subarachnoid obstruction Late and postponed 77.7%. Pulmonary tuberculosis in 20 cases, of which 3 cases of primary, blood stenosis in 16 cases, infiltration in 1 case. Treatment regimen SM0.75 1 intramuscular injection, INH0.3 hair circumference albumin and 0.6 ~ 0.9, PZA0.5 3 times orally. Children reduce the dosage; all with flumethasone intravenous infusion 0.1 ~ 0.2mg / kg; 3 cases of spinal administration of dexamethasone, 10 cases have been added with RFP. Reported in the literature, the use of hydrogen or hydrocortisone, and advocated 1 month after the start of reduction, treatment no more than 3 months. This group of application of flumethasone is in the cerebrospinal