硬皮病是一种很少见疾病,国內少有报告,今年作者偶发现一例,症状甚为特殊,特予报道。病例报告張某,女性,21岁,家务,住院号161,一九五八年九月三日入院,入院主訴:上肢胸背部皮肤发硬已一年余。患者一九五七年三月发病,开始自觉二手指关节,腕关节发硬,运动不灵活, Scleroderma is a rare disease, rare domestic reports, this year, the author found a case of even the symptoms are very special, especially to be reported. Case report Zhang, female, 21 years old, housework, hospitalization 161, admitted on September 3, 1958, admitted to the hospital: the chest and back of the upper limbs hair stiff more than a year. Patients in March 1957 the onset, began to consciously secondhand knuckles, wrist hard, exercise is not flexible,